by GRUNE & STRATTON .
Written in English
|The Physical Object|
|Number of Pages||56|
Aminoglutethimide may be taken with or without food. Aminoglutethimide will initially be given in a hospital setting by a health care provider who is familiar with its use. If you miss a dose of aminoglutethimide, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Aminoglutethimide interferes with the body's production of certain hormones. Aminoglutethimide is used in the treatment of conditions which cause the body to make too much of certain hormones (Cushing's syndrome). Aminoglutethimide may also be used for purposes other than those listed in this medication guide. 1. Acta Clin Belg Suppl. ; Aminoglutethimide: chemistry, pharmacokinetics, pharmacology and mechanism of action. Nadjafi C. PMID:Cited by: 3. 1. Pharmacotherapy. Sep-Oct;1(2) Aminoglutethimide: review of pharmacology and clinical use. Santen RJ, Misbin RI. Aminoglutethimide blocks several cytochrome P mediated steroid hydroxylation steps, including those required for conversion of cholesterol to pregnenolone and for the aromatization of androgens to estrogens.
CYTADREN® Novartis Pharmaceuticals. Aminoglutethimide. Adrenal Suppressant – Reversible Inhibitor of Peripheral Estrogen Synthesis. Action And Clinical Pharmacology: Cushing’s Syndrome: Aminoglutethimide is a potent reversible inhibitor of adrenal mineralocorticoid and glucocorticoid synthesis. It partially inhibits the enzymatic conversion of cholesterol to pregnenolone, the reaction. Aminoglutethimide (AG), sold under the brand names Elipten, Cytadren, and Orimeten among others, is a medication which has been used in the treatment of seizures, Cushing's syndrome, breast cancer, and prostate cancer, among other indications. It has also been used by bodybuilders, athletes, and other men for muscle-building and performance- and physique-enhancing purposes. DL-Aminoglutethimide is a derivative of the sedative glutethimide. Originally introduced as an anticonvulsant, it was found to cause adrenal insufficiency. Blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of cholesterol to pregnenolone. It also blocks the peripheral conversion (aromatization) of androgenic precursors to. Aminoglutethimide is a synthetic derivative of the sedative and anticonvulsant glutethimide with anti-steroid properties. Originally used as an anticonvulsant, aminoglutethimide also blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of cholesterol to addition, this agent blocks the peripheral aromatization of androgenic precursors to estrogens.
aminoglutethimide is a topic covered in the Davis's Drug Guide.. To view the entire topic, please sign in or purchase a subscription.. Nursing Central is an award-winning, complete mobile solution for nurses and students. Look up information on diseases, tests, and procedures; then consult the database with 5,+ drugs or refer to 65,+ dictionary terms. aminoglutethimide is a topic covered in the Davis's Drug Guide. To view the entire topic, please sign in or purchase a subscription. The Washington Manual of Medical Therapeutics helps you diagnose and treat hundreds of medical conditions. Consult clinical recommendations from a resource that has been trusted on the wards for 50+ years. Aminoglutethimide accelerates its own metabolism from a basal value of ± (S.E.) liters/24 hours to ± liters/24 hours after 1 to 2 weeks of Aminoglutethimide administration, and markedly accelerates the metabolism of the synthetic glucocorticoid and dexamethasone, from basal values of ± liters/24 hours to ± liters/ Aminoglutethimide. London: Royal Society of Medicine ; New York: Grune & Stratton, (OCoLC) Document Type: Book: All Authors / Contributors: R W Elsdon-Dew; I M Jackson; G F B Birdwood; Royal Society of Medicine (Great Britain).